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DSIR Recognized | FWA Approved - FWA00012971

The Effect of Zinc & Copper Supplement in Acute Diarrhea in Children Aged 5-59 Months: Randomized Controlled Trial

Diarrhea causes an estimated 2.5 million child deaths in developing countries each year, 35% of which are due to acute diarrhea. Zinc and copper stores in the body are known to be depleted during acute diarrhea. Our objectives were to evaluate the efficacy of zinc and copper supplementation when given with standard treatment to children with acute watery or bloody diarrhea.

Investigating Team

  • Dr. Archana Patel
  • Dr. Michael J. Dibeley
  • Manju Mamtani
  • Neetu Bhadoniya
  • Dr. Hemant Kulkarni

Welcome Trust Collaborative Research institute Grant (Number68664/Z/02/Z)

The expected beneficial effects of zinc supplementation for acute diarrhea were not observed. Therapeutic Zn or Zn and Cu supplementation may not have a universal beneficial impact on the duration of acute diarrhea in children.

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Background & Objective

The Effect of Zinc & Copper Supplement in Acute Diarrhea in Children Aged 5-59 Months: Randomized Controlled Trial

Diarrhea causes an estimated 2.5 million child deaths in developing countries each year, 35% of which are due to acute diarrhea. Zinc and copper stores in the body are known to be depleted during acute diarrhea. Our objectives were to evaluate the efficacy of zinc and copper supplementation when given with standard treatment to children with acute watery or bloody diarrhea.

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Team

Investigating Team

  • Dr. Archana Patel
  • Dr. Michael J. Dibeley
  • Manju Mamtani
  • Neetu Bhadoniya
  • Dr. Hemant Kulkarni
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Supported By

Welcome Trust Collaborative Research institute Grant (Number68664/Z/02/Z)

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Conclusion

The expected beneficial effects of zinc supplementation for acute diarrhea were not observed. Therapeutic Zn or Zn and Cu supplementation may not have a universal beneficial impact on the duration of acute diarrhea in children.

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Timeline
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